Kinetics of methaemoglobin and serum nitrogen oxide production during inhalation of nitric oxide in volunteers

Serum nitrogen oxides during nitric oxide inhalation.

A patient with acute respiratory failure secondary to leptospirosis was treated with 40 and 90 volumes per million inhaled nitric oxide. His serum nitrogen oxide concentration (nitrates and nitrites combined) increased 13-fold. The mechanisms for the formation and elimination of nitrates are discussed.

Kinetics of Nitric Oxide Production and MTT Reduction by HSV-1 Infected Macrophages

Background: Macrophages have important role in defense against Herpes Simplex Virus type-1 (HSV-1). The present study was performed to determine the viability and nitric oxide (NO) production by HSV-1 infected mouse peritoneal macrophages (HIM). Method: The viability of macrophages was evaluated using MTT reduction assay and the production of nitrite using Griess method. Results: The ability of...

Nitric Oxide Production and Nitric Oxide

Monitoring of Serum Nitric oxide in Patients with Acute Leukemia

Nitric oxide (NO) is a molecule required for many physiological functions, produced from L-arginine by NO synthases (NOS). It is a free radical, producing many reactive intermediates that account for its bioactivity. Sustained induction of the inducible form of NOS (iNOS) in chronic inflammation may be mutagenic, through NO-mediated DNA damage or hindrance to DNA repair, and thus potentially ca...

Monitoring of Serum Nitric oxide in Patients with Acute Leukemia

Nitric oxide (NO) is a molecule required for many physiological functions, produced from L-arginine by NO synthases (NOS). It is a free radical, producing many reactive intermediates that account for its bioactivity. Sustained induction of the inducible form of NOS (iNOS) in chronic inflammation may be mutagenic, through NO-mediated DNA damage or hindrance to DNA repair, and thus potentially ca...